Key result
Among patients receiving ECLS for refractory cardiac arrest or shock, drug intoxication as the etiology was strongly associated with survival (AOR 0.07; 95% CI 0.01-0.28; p<0.001).
Why the study?
What factors are associated with hospital mortality in patients receiving extracorporeal life support for refractory cardiac arrest or shock?
Population
64 consecutive patients treated with extracorporeal life support for refractory cardiac arrest or shock…
Design
Cohort
Follow-up
Until hospital discharge
Authors
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Drug intoxication etiology and higher pH at ECLS start associated with survival; hypothesis-generating for selection criteria in refractory arrest or shock.
Cohort (n=64)
No
What factors are associated with hospital mortality in patients receiving extracorporeal life support for refractory cardiac arrest or shock?
Odds Ratio: 0.07 (95% CI 0.01–0.28)
p-value: p=< 0.001
In patients receiving ECLS for refractory cardiac arrest or shock, reversible causes such as drug intoxication and less severe initial acidosis are strongly associated with improved survival.
Brunet et al. (2015) conducted a cohort in Refractory cardiac arrest or shock (n=64). Drug intoxication as reason for ECLS vs. Other reasons for ECLS was evaluated on Survival (AOR 0.07, 95% CI 0.01-0.28, p=< 0.001). Among patients receiving ECLS for refractory cardiac arrest or shock, drug intoxication as the etiology was strongly associated with survival (AOR 0.07; 95% CI 0.01-0.28; p<0.001).
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