Key result
High sodium dialysate reduced the incidence of ischemic EKG changes compared to standard sodium dialysate (27.9% vs 60.5%) in hemodialysis patients.
Why the study?
Does high sodium dialysate reduce EKG signs of myocardial ischemia in hemodialysis patients compared to standard sodium dialysate?
Does high sodium dialysate reduce EKG signs of myocardial ischemia in hemodialysis patients compared to standard sodium dialysate?
Using a relatively high sodium dialysate during hemodialysis may reduce the incidence of EKG-detected myocardial ischemia and disequilibrium syndrome compared to standard sodium dialysate.
Answers are grounded in this paper and cite their sources.
High-sodium dialysate merits randomized evaluation to reduce intradialytic ischemia; should not yet change practice.
This study was undertaken to evaluate the effect of increasing the dialysate sodium concentration on myocardial ischemia assessed by EKGs taken immediately before and after dialysis in 43 hemodialysis patients. An increase in the R wave (V5 + V6) by more than 5 mm was seen in 26 patients with standard sodium dialysate, while only 12 cases showed the same changes after a high sodium dialysis. These was a positive correlation between an increase in R wave amplitude and the weight loss/dry weight ratio of patients only after standard sodium dialysis (r = 0.74, p less than 0.001). Relative high sodium dialysate is beneficial during dialysis and reduce the incidence of myocardial ischemia and unpleasant disequilibrium syndrome.
No takes yet. Share an insight, caveat, or question.
Ono et al. (2008) studied Hemodialysis (n=43). High sodium dialysate vs. Standard sodium dialysate was evaluated on Increase in the R wave (V5 + V6) by more than 5 mm. High sodium dialysate reduced the incidence of ischemic EKG changes compared to standard sodium dialysate (27.9% vs 60.5%) in hemodialysis patients.
Synapse has enriched 10 related papers. Consider them for comparative context: