Key result
The Kir4.1 gene product forms an inward rectifier potassium channel, or is a subunit of the channel, in mouse cortical astrocytes both in culture and in vivo.
Population
Mouse cortical and white matter astrocytes, adult mouse brain tissue, and HEK cells
Comparison
In vitro cell culture conditions and… vs Control culture conditions (e.g., confluent cells)
Design
Preclinical
Authors
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No immediate clinical implications; leaves open Kir4.1's role in human astrocytic K+ buffering or disease.
The Kir4.1 gene product forms an inward rectifier potassium channel in mouse cortical astrocytes.
Li et al. (2001) studied this question. The Kir4.1 gene product forms an inward rectifier potassium channel, or is a subunit of the channel, in mouse cortical astrocytes both in culture and in vivo.
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