Answers are grounded in this paper and cite their sources.
An efficient nickel-catalyzed C-H trifluoromethylation for the synthesis of trifluoromethylated free anilines using Togni's reagent has been developed. This approach exhibits a good functional group tolerance, good regioselectivity, and chemoselectivity under mild conditions. The newly developed economical one-step method is a better alternative to synthesize trifluoromethylated free anilines.
No takes yet. Share an insight, caveat, or question.
Gao et al. (2018) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: