Key result
Resection of an incidental right ventricular mass in a 36-year-old woman confirmed the rare diagnosis of benign metastasizing leiomyoma of the heart.
Case Report (n=1)
This case highlights the rare occurrence of benign metastasizing leiomyoma presenting as a cardiac mass in the right ventricle.
May support inclusion of benign metastasizing leiomyoma in right ventricular mass differentials; extends known metastatic sites but remains hypothesis-generating.
Uterine leiomyomas are the most common gynecological tumors in premenopausal women. While the lung is the most common extrauterine organ afflicted, benign metastasizing leiomyomas (BML) of the heart are rarities. We report an incidental finding of a cardiac mass in a 36-year-old woman who presented to the Emergency Department after a motor vehicle accident. CT scan of the chest revealed 2 well-circumscribed pulmonary nodules and a filling defect in the right ventricle. Echocardiogram showed a 4 cm mass attached to the right ventricular (RV) septum. The cardiac tumor was resected and showed benign histologic features. Immunohistochemical staining was positive for smooth muscle α-actin and desmin, as well as estrogen and progesterone receptors, consistent with the diagnosis of uterine leiomyoma.
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Meddeb et al. (2018) conducted a case report in Benign metastasizing leiomyoma of the heart (n=1). Tumor resection was evaluated on Pathological diagnosis. Resection of an incidental right ventricular mass in a 36-year-old woman confirmed the rare diagnosis of benign metastasizing leiomyoma of the heart.
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