Key result
Self-curing methyl methacrylate use in ophthalmic surgery has no reported cardiovascular complications, despite more than 20 deaths associated with its use in orthopedic surgery.
Why the study?
Does self-curing methyl methacrylate cause cardiovascular complications in ophthalmic surgery?
Does self-curing methyl methacrylate cause cardiovascular complications in ophthalmic surgery?
Despite cardiovascular collapse risks in orthopedic surgery, there is no evidence to condemn the use of self-curing methyl methacrylate in ophthalmic surgery.
No reported events support safety in ophthalmic use; leaves open need for prospective data on rare events.
Self-curing methyl methacrylate has been recently abandoned by some ophthalmic surgeons because of more than 20 deaths associated with its use in orthopedic surgery. The mechanism of cardiovascular collapse noted in orthopedic cases appears to relate to the surgical procedure as well as a direct vasodilation caused by free monomer. There are no reported cardiovascular complications with the facial uses of self-curing methyl methacrylate. Toxicities to this substance are noted. Ophthalmologists should be aware of these problems and their management. Careful preoperative cardiovascular evaluation, intraoperative patient monitoring, and a well-ventilated operating room are recommended with its use. The review finds no evidence to condemn the ophthalmic uses of self-curing methyl methacrylate because of cardiovascular complications. The search for more inert synthetic compounds should continue.
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Anderson et al. (1976) conducted a review in Ophthalmic surgery. Self-curing methyl methacrylate was evaluated on Cardiovascular complications. Self-curing methyl methacrylate use in ophthalmic surgery has no reported cardiovascular complications, despite more than 20 deaths associated with its use in orthopedic surgery.
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