Analgesic Nephropathy and Urinary-Tract Carcinoma

Editorial Notes1 March 1979Analgesic Nephropathy and Urinary-Tract CarcinomaTHOMAS A. GONWA, M.D., VARDAMAN M. BUCKALEW JR., M.D., WAYNE T. CORBETT, DR. PH, V. M. D.THOMAS A. GONWA, M.D.Search for more papers by this author, VARDAMAN M. BUCKALEW JR., M.D.Search for more papers by this author, WAYNE T. CORBETT, DR. PH, V. M. D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-3-432 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMost nephrologists now recognize that excessive use of analgesics can lead to the development of chronic renal failure, although many other physicians continue to be unaware of the problem. That analgesic-associated nephropathy is an international problem was made clear in a recent symposium (1). Whether analgesic abuse is a major cause of renal disease in the United States is still open to question (2) and needs further study.The increased incidence of urinary-tract carcinoma among analgesic abusers is sometimes overlooked. In 1965, Hultengren, Lagergren, and Ljungqvist (3) first called attention to this association. They reported a series of 103 patients...References1. KINCAID-SMITH P: Symposium on analgesic nephropathy. Kidney Int 13:1-113, 1978 CrossrefMedlineGoogle Scholar2. GOLDBERGMURRAY MT: Analgesic-associated nephropathy. An important cause of renal disease in the United States? N Engl J Med 299:716-717, 1978 CrossrefMedlineGoogle Scholar3. HULTENGRENLAGERGRENLJUNQVIST NLA: Carcinoma of the renal pelvis in renal papillary necrosis. Acta Chir Scand 130:314-320, 1965 MedlineGoogle Scholar4. BENGTSSONANGERVALLEKMANLEHMANN ULHL: Transitional cell tumors of the renal pelvis in analgesic abusers. Scand J Urol Nephrol 2:145-150, 1968 CrossrefMedlineGoogle Scholar5. ANGERVALLBENGTSSONZETTERLUNDZSIGMOND LUCM: Renal pelvis carcinoma in a Swedish district with abuse of a phenacetin-containing drug. Br J Urol 41:401-405, 1969 CrossrefMedlineGoogle Scholar6. BENGTSSONJOHANSSONANGERVALL USL: Malignancies of the urinary tract and their relation to analgesic abuse. Kidney Int 13:107-113, 1978 CrossrefMedlineGoogle Scholar7. MANNIONSUSMANO RD: Phenacetin abuse causing bladder tumor. J Urol 106:692, 1971 CrossrefMedlineGoogle Scholar8. TOSIMORIN SL: Bladder tumor associated with phenacetin abuse. Urology 9:59-60, 1977 CrossrefMedlineGoogle Scholar9. JOHANSSONANGERVALLBENGTSSONWAHLQVIST SLUL: Uroepithelial tumors of the renal pelvis associated with abuse of phenacetin-containing analgesics. Cancer 33:743-753, 1974 CrossrefMedlineGoogle Scholar10. JOHANSSONANGERVALLBENGTSSONWAHLQVIST SLUL: A clinicopathologic and prognostic study of epithelial tumors of the renal pelvis. Cancer 37:1376-1383, 1976 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bowman Gray School of Medicine Wake Forest University Winston-Salem, North Carolin PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGenotoxicity of analgesic compounds assessed by an in vitro micronucleus assayHematuriaSquamous cell carcinoma of the renal pelvis as a late complication of hepatic irradiation: A case reportDrug Information Analysis ServicePaperChase: A Computer Program to Search the Medical LiteratureAnalgesic-Associated Nephropathy and Transitional Cell Carcinoma of the Urinary TractTHOMAS A. GONWA, M.D., WAYNE T. CORBETT, V.M.D., Dr. P.H., HARRY M. SCHEY, Ph.D., VARDAMAN M. BUCKALEW Jr., M.D.Bladder Carcinoma and PhenacetinTHOMAS E. BURKART, M.D.Analgesic-Associated Urinary-Tract TumorsKEITH R. BURNETT, M.D., J. BERNARD MILLER, M.D., EDWARD GREENBAUM, M.D. 1 March 1979Volume 90, Issue 3Page: 432-433KeywordsAnalgesicsRenal diseasesRenal failure Issue Published: 1 March 1979 PDF downloadLoading ...