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September 5, 2026Cardiology in the Young

CardioFusion-XAI: a robust multi-scale and explainable framework for cardiac MRI-based disease classification

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Authors

SBShwetambari BoradeSMSaraswati MishraRVRupali Vairagade

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Overview

Validation study demonstrates high classification accuracy for cardiac MRI scans, indicating potential for automated cardiovascular disease diagnosis.

Key Points

  • Develop and evaluate an explainable multi-scale deep learning framework (CardioFusion-XAI) to improve the accuracy and interpretability of four-class cardiac MRI disease classification.
  • Integrated WaveCLAHE-Net, which combines wavelet-based enhancement and contrast-limited adaptive histogram equalization, to preprocess and enhance image quality.
  • Constructed CardioXtract Fusion Net combining ResNet-50, EfficientNet-B0, and a Vision Transformer to capture local, multi-scale, and global features.
  • Evaluated performance on the Sunnybrook Cardiac Dataset and implemented Grad-CAM and t-distributed stochastic neighbour embedding for model interpretability.
  • CardioFusion-XAI achieved an overall classification accuracy of 98.89% and an area under the curve of 0.9998 on the Sunnybrook Cardiac Dataset.
  • The framework demonstrated a precision of 98.93% and an F1-score of 98.90% across the four cardiac disease classes.

Cite This Study

Borade et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd4606b95aff0620ec0a7https://doi.org/10.1017/s1047951126123671
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