What does this research mean for the field?

HHV-6 reactivation is frequent in pediatric patients following allogeneic hematopoietic stem cell transplantation, typically occurring between 12 and 25 days post-transplant regardless of sex, donor relationship, or transplant type. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To determine the frequency, timing, and associated risk factors of human herpesvirus 6 detection in paediatric patients during the first 30 days after allogeneic haematopoietic stem cell transplantation.

September 5, 2026South Asian Journal of CancerOpen Access

Detection of human herpesvirus 6 in paediatric patients after haematopoietic stem cell transplantation: A retrospective cohort study

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Authors

MMMaría Estela Hernández Meza AZAndrea De María Zavaleta-González CÁCarla Celinda Álvarez-Chacón

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Implication

Retrospective cohort study observes frequent human herpesvirus 6 reactivation in paediatric stem cell recipients, highlighting a critical monitoring window during initial post-transplant weeks.

Key Points

To determine the frequency, timing, and associated risk factors of human herpesvirus 6 detection in paediatric patients during the first 30 days after allogeneic haematopoietic stem cell transplantation.
Retrospective cohort study evaluating 51 paediatric patients who underwent allogeneic haematopoietic stem cell transplantation.
Conducted real-time polymerase chain reaction testing to detect human herpesvirus 6 during the initial 30 days post-transplantation.
Analysed time-to-detection via Kaplan–Meier curves and Cox proportional hazards models across sex, donor relationship, and transplant type.
Human herpesvirus 6 was detected in 19 of 51 patients (37.3%) within the first 30 days after transplantation.
Viral detection events clustered predominantly between days 12 and 25 following the transplant procedure.
No statistically significant differences in viral detection rates were observed based on sex, donor relationship, or transplant type.

Cite This Study

Meza et al. (2026) studied this question.

synapsesocial.com/papers/6a9bd49d6b95aff0620ec600 https://doi.org/10.25259/sajc_51_2026

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Implication

Retrospective cohort study observes frequent human herpesvirus 6 reactivation in paediatric stem cell recipients, highlighting a critical monitoring window during initial post-transplant weeks.

Detection of human herpesvirus 6 in paediatric patients after haematopoietic stem cell transplantation: A retrospective cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

Detection of human herpesvirus 6 in paediatric patients after haematopoietic stem cell transplantation: A retrospective cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

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