Key result
Thromboprophylaxis after total knee or hip replacement was used for a mean of 30 days, with 1% to 2% of patients hospitalized for VTE, major bleeding, or wound infections during 3 months of follow-up.
Population
8,551 adults ≥ 18 years hospitalized for total knee replacement, total hip replacement without hip fracture…
Design
Cohort
Follow-up
3 months
Authors
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Low event rates with 30-day use extend real-world data; should not yet change practice.
Cohort (n=8,551)
Real-world thromboprophylaxis after total knee and hip replacement in the Netherlands demonstrates low rates of VTE and major bleeding hospitalizations, though most VTEs still occur while on treatment.
Beest et al. (2011) conducted a cohort in Total knee replacement (TKR) or total hip replacement (THR) (n=8,551). Thromboprophylaxis was evaluated on Hospitalization for venous thromboembolism (VTE), major bleeding, and wound infections. Thromboprophylaxis after total knee or hip replacement was used for a mean of 30 days, with 1% to 2% of patients hospitalized for VTE, major bleeding, or wound infections during 3 months of follow-up.
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