Long‐term clinical outcomes of the Toronto stentless porcine valve: 15‐year results from dual centers
Key result
The Toronto stentless porcine valve showed excellent early durability, but the cumulative incidence of repeated AVR increased to 34.4% (95% CI 28.8-40.2) at 15 years.
Why the study?
The study was conducted to examine the long-term durability of the Toronto stentless porcine valve in the aortic position.
What is the long-term durability and survival associated with the Toronto stentless porcine valve in patients undergoing aortic valve replacement?
Population
515 patients undergoing AVR with the Toronto SPV, excluding early death
Design
Dual-center observational cohort study
Follow-up
Median 11.5 years
Authors
Discussion
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Member takes
Implication
Warrants caution with lifelong monitoring after Toronto stentless implantation; leaves open comparative durability versus other valves in randomized data.
Study Design
Type
Cohort (n=515)
Multicenter
Yes
Structured PICO
What is the long-term durability and survival associated with the Toronto stentless porcine valve in patients undergoing aortic valve replacement?
P
Population
515 patients who underwent aortic valve replacement with the Toronto stentless porcine valve, excluding early deaths, followed for a median of 11.5 years.
E
Exposure
Aortic valve replacement with the Toronto stentless porcine valve (SPV)
O
Outcome
Long-term durability and clinical outcomes including overall survival and cumulative incidence of repeated AVRhard clinical
The Toronto stentless porcine valve provides excellent survival and durability in the first decade, but structural valve deterioration (primarily regurgitation) increases significantly after 10 years, requiring reoperation in over a third of patients by 15 years.
Cite This Study
Une et al. (2020) conducted a cohort in Aortic valve replacement (n=515). Toronto stentless porcine valve (SPV) was evaluated on Cumulative incidence of repeated AVR at 15 years (95% CI 28.8-40.2). The Toronto stentless porcine valve showed excellent early durability, but the cumulative incidence of repeated AVR increased to 34.4% (95% CI 28.8-40.2) at 15 years.