Key result
Lower lymphocyte-to-monocyte ratio (LMR) was identified as an independent predictor of severe calcific aortic valve stenosis, showing an inverse correlation with stenosis severity.
Why the study?
This study examined the role of lymphocyte-to-monocyte ratio (LMR), an inflammatory biomarker, in predicting the severity of calcific aortic valve stenosis (CAVS).
Does the lymphocyte-to-monocyte ratio (LMR) predict the severity of calcific aortic valve stenosis (CAVS) in Chinese patients?
Case-Control
Does the lymphocyte-to-monocyte ratio (LMR) predict the severity of calcific aortic valve stenosis (CAVS) in Chinese patients?
Answers are grounded in this paper and cite their sources.
The lymphocyte-to-monocyte ratio is inversely correlated with the severity of calcific aortic valve stenosis and may serve as an independent predictor of severe disease.
Aim: This study examined the role of lymphocyte-to-monocyte ratio (LMR), an inflammatory biomarker, in predicting the severity of calcific aortic valve stenosis (CAVS) in a Chinese case–control study. Results: The LMR significantly decreased in the patients with CAVS compared with healthy controls. An inverse correlation was observed between the severity of stenosis and LMR in the patients. Additionally, the LMR was identified in the multivariate analysis as an independent predictor of severe CAVS. Conclusion: This study provides evidence of an inverse correlation between the severity of CAVS and LMR. LMR could potentially be applied as an independent predictor of severe CAVS and could be incorporated into a novel predictive model.
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Ma et al. (2020) conducted a case-control in Calcific aortic valve stenosis. Lymphocyte-to-monocyte ratio (LMR) vs. Healthy controls was evaluated on Severity of calcific aortic valve stenosis. Lower lymphocyte-to-monocyte ratio (LMR) was identified as an independent predictor of severe calcific aortic valve stenosis, showing an inverse correlation with stenosis severity.
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