Key result
Minimal hepatic encephalopathy in cirrhotic patients was associated with lower EEG alpha wave frequency and amplitude compared to healthy controls.
Why the study?
Do EEG alpha wave patterns differ in patients with cirrhosis and minimal hepatic encephalopathy compared to healthy controls?
Case-Control (n=140)
No
Do EEG alpha wave patterns differ in patients with cirrhosis and minimal hepatic encephalopathy compared to healthy controls?
EEG alpha wave morphology (frequency < 10 Hz and amplitude < 40 µV) can potentially supplement other diagnostic tests for minimal hepatic encephalopathy in patients with cirrhosis.
Answers are grounded in this paper and cite their sources.
Multiple tests for MHE diagnosis in cirrhosis leave open the optimal standardized approach; prospective validation required.
Background: Minimal Hepatic Encephalopathy (MHE) is now increasingly described in patients with cirrhosis without any overt abnormalities on clinical examination. The diagnosis of MHE is based on multiple tests including a combination of paper and pencil tests, computerised tests and neurophysiological tests.
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Swami et al. (2018) conducted a case-control in Cirrhosis and Minimal Hepatic Encephalopathy (n=140). Minimal Hepatic Encephalopathy vs. Healthy controls was evaluated on Alpha wave frequency (Hz) (p=<0.05). Minimal hepatic encephalopathy in cirrhotic patients was associated with lower EEG alpha wave frequency and amplitude compared to healthy controls.
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