Key result
Finapres arterial pulse wave analysis with Modelflow significantly underestimated cardiac output compared to thermodilution (4.7 vs 6.4 L/min, P<0.001) and showed no significant correlation.
Why the study?
Does Finapres arterial pulse wave analysis with Modelflow accurately measure cardiac output compared to invasive thermodilution in healthy elderly subjects?
Population
28 healthy elderly subjects, mean age 70±4 years.
Comparison
Finapres arterial pulse wave analysis with… vs Thermodilution cardiac output measured during…
Design
Cross-sectional
Authors
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May caution against Finapres Modelflow for cardiac output in elderly without calibration; leaves open accuracy in broader populations.
Observational (n=28)
Does Finapres arterial pulse wave analysis with Modelflow accurately measure cardiac output compared to invasive thermodilution in healthy elderly subjects?
Mean Difference: -1.7
Absolute Event Rate: 4.7% vs 6.4%
p-value: p=<0.001
Non-invasive cardiac output measurement using Finapres with Modelflow is inaccurate in healthy elderly subjects and should not be used without invasive calibration.
REMMEN et al. (2002) conducted an observational in Healthy elderly subjects (n=28). Finapres arterial pulse wave analysis with Modelflow vs. Thermodilution was evaluated on Cardiac output (litres/min) (MD -1.7, 95% CI -4.6 to +1.1, p=<0.001). Finapres arterial pulse wave analysis with Modelflow significantly underestimated cardiac output compared to thermodilution (4.7 vs 6.4 L/min, P<0.001) and showed no significant correlation.
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