The alcohol extract of the whole plant of Enicostemma littorale. Blume was evaluated for its antihepatotoxic activity against CCl4-induced hepatic damage in rats. The activity was evaluated by using biochemical parameters, such as serum glutamate pyruvate transaminase, serum glutamate oxaloacetate transaminase, alkaline phosphatase, total bilirubin, and γ.-glutamate transpeptidase. The histopathological changes of liver sample were compared with respective controls. The extract showed a remarkable hepatoprotective effect.
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Senthilkumar et al. (2005) studied this question.
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