Key result
Right ventricular dysfunction, pulmonary hypertension, and altered RV-arterial coupling upon admission were associated with increased in-hospital mortality (overall rate 37.6%) in COVID-19 patients.
Why the study?
COVID-19 frequently involves cardiovascular manifestations, prompting evaluation of the ORACLE critical care ultrasonography protocol to identify frequent alterations and their impact on adverse outcomes.
Do right ventricular dysfunction and right ventricular-arterial uncoupling at admission increase in-hospital mortality in adult patients with COVID-19?
Cross-Sectional (n=204)
Yes
Do right ventricular dysfunction and right ventricular-arterial uncoupling at admission increase in-hospital mortality in adult patients with COVID-19?
Echocardiographic evidence of right ventricular dysfunction, pulmonary hypertension, and right ventricular-arterial uncoupling at admission identifies COVID-19 patients at increased risk of in-hospital mortality.
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RV dysfunction and PH on admission were associated with higher COVID-19 mortality; leaves open whether routine screening or targeted therapy improves outcomes.
Manzur‐Sandoval et al. (2021) conducted a cross-sectional in COVID-19 (n=204). Right ventricular dysfunction, pulmonary hypertension, and altered RV-arterial coupling was evaluated on In-hospital mortality. Right ventricular dysfunction, pulmonary hypertension, and altered RV-arterial coupling upon admission were associated with increased in-hospital mortality (overall rate 37.6%) in COVID-19 patients.
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