"Intravascular coagulation"1-5has repeatedly been incriminated for the hemorrhagic diathesis associated with giant hemangiomas originally described by Kasabach and Merritt in 1940.6The reversal of the abnormalities by anticoagulants1and survival studies with labeled fibrinogen5,8have firmly established its pathogenetic role. In the present report a massive preferential accumulation of the radioactivity of fibrinogen tagged with iodine 131 in the region of a giant hemangioma is documented, suggesting a localized rather than a generalized intravascular consumption of fibrinogen in this disorder.
No takes yet. Share an insight, caveat, or question.
P W Straub (1972) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: