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LINICAL investigation of malignant mela-C noma has gained considerable impetus within recent years.Numerous reports have appeared describing anatomical incidence,l" theories of histogenesis,l and modern concepts of treat111ent.l~These articles have two objectives: better understanding of the natural history of the disease and improvement in diagnosis and therapy.l h e purpose of this presentation is to summarize the experience of hlcniorial Center with melanoma when it occurred primarily in the mucous membranes of the oral cavity or upper respiratory tract.The report covers nineteen years, between 1930 and 1948 inclusive.Rarity of nielanoma in the oral cavity or upper respiratory tract limits the experience of the individual clinician.For this reason a review of the incidence, symptomatology, treatment, and results of the Memorial Center cases appears indicated.Twenty-six such cases are analyzed.
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Moore et al. (1955) studied this question.
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