Eco-friendly and facile production method, natural products chemistry, and pharmacological properties of silver nanoparticles using telfaria occidentalis leaf and stem extracts

Using an extract from telfairia occidentalis leaves and stems, this work aims to provide an easy and environmentally friendly method to synthesize silver nanoparticles (AgNPs). Furthermore, the research will examine the extract’s natural products chemistry and evaluate its possible anti-inflammatory, anti-diabetic, antioxidant, and antiglycation effects. The silver nanoparticles were characterized through ultraviolet-visible spectroscopy, Fourier transform infrared, and scanning electron microscopy (SEM). The antioxidant, anti-diabetic, and anti-inflammatory activities were conducted using various methods under standard conditions. The visual color change observed indicated the presence of synthesized AgNPs. The creation of silver nanoparticles was verified by surface plasmon resonance scan, which revealed that the nanoparticles had absorption peak at 400 nanometers. Additionally, SEM results provided insights into the size distribution of the AgNPs, ranging from 22 nm-68 nm, 43.66 nm mean. The study suggests that the extract from telfairia occidentalis leaf and stem has the potential to produce AgNPs with antioxidant, anti-inflammatory, anti-diabetic and anti-glycation uses. AgNPs may be valuable in the development of drugs for diabetes treatment and management.