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Bacterial proteins in the haystack: The alkynyl amino acid reporter AOA (see scheme) can be used to visualize and identify newly synthesized bacterial proteins during Salmonella infection of mammalian cells by the copper(I)-catalyzed azide–alkyne cycloaddition. This technique opens new opportunities for the system-wide analysis of bacterial pathogens.
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Grammel et al. (2010) studied this question.
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