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The effects of adriamycin, 5-fluorouracil, methotrexate, triamcinolone and Viroptic on an experimental model of proliferative vitreoretinopathy (PVR) produced by the injection of homologous dermal fibroblasts into the rabbit vitreous were studied. Adriamycin and fluorouracil inhibited fibroblast proliferation and prevented the formation of membranes as well as did triamcinolone, whereas methotrexate and Viroptic had no beneficial effect in this model of PVR.
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Sunalp et al. (1984) studied this question.
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