Aregenerative Anemia Associated with Benign Thymoma

FOURTEEN cases of aregenerative anemia associated with benign thymoma have been reported to date in the medical literature.1 2 3 4 5 6 7 8 9 10 11 The present report adds 2 cases of the syndrome and describes an experimental attempt to produce anemia with an extract of the thymoma from 1 of the patients.The report of Humphreys and Southworth5 in 1945 first emphasized the fact that the association of thymoma and aregenerative anemia could not be ascribed to chance. They reported the case of a fifty-eight-year-old woman with a large mediastinal tumor that was unresponsive to irradiation. Two years after discovery of the tumor, a severe refractory . . .