Key result
A non-dipping blood pressure pattern was observed in 65% of hypertensive patients and 38% of normotensive individuals, indicating altered circadian rhythms in both groups.
Why the study?
Despite its clinical utility for masked/white coat hypertension, assessing allostatic load, and guiding chronotherapy, 24-hour BP monitoring is sparingly used clinically. The study explored circadian BP variations in normotensive and hypertensive Indians.
Cross-Sectional (n=100)
No
Absolute Event Rate: 65% vs 38%
Altered circadian blood pressure patterns, particularly non-dipping status, are prevalent in both normotensive and hypertensive Indian adults, highlighting the utility of 24-hour ABPM for early detection and chronotherapy.
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Non-dipping patterns may support broader ABPM screening in normotensives; leaves open prospective outcome trials on chronotherapy.
Khatri et al. (2022) conducted a cross-sectional in Hypertension (n=100). Hypertension vs. Normotension was evaluated on Non-dipping blood pressure pattern. A non-dipping blood pressure pattern was observed in 65% of hypertensive patients and 38% of normotensive individuals, indicating altered circadian rhythms in both groups.
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