Key result
Electrical cardioversion and curative WPW ablation resolve VT after failed medical therapy in a quetiapine user.
Case Report (n=1)
No
In a patient presenting with ventricular tachycardia while on quetiapine, early electrical cardioversion and subsequent electrophysiological study successfully identified and treated underlying Wolff-Parkinson-White syndrome.
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May support early electrical cardioversion after failed drugs in quetiapine-associated VT; hypothesis-generating for WPW as treatable substrate.
Ventricular tachycardia (VT) is a mortal rhythm that can occur for many reasons. Wolff Parkinson White (WPW) syndrome can cause VT. Although there are usually signs and symptoms specific to underlying diseases, sometimes it may not be possible to make a differential diagnosis. A 32-year-old male presented to the emergency department with complaints of sudden onset of palpitations and weakness. He was using quetiapine in history. His hemodynamic were stable and his rhythm on the electrocardiogram (ECG) was evaluated as VT. Medical cardioversion was started with amiodarone. Electrical cardioversion was performed after the development of nausea, dizziness, and chest pain symptoms, and a return to normal sinus rhythm was achieved. There were no typical findings in the control ECG showing WPW syndrome or the effect of Quetiapine. The diagnosis of WPW was confirmed by an electrophysiological study (EPS), and successful treatment was performed by catheter ablation. Early electrical cardioversion may be considered when there is no response to medical cardioversion in the acute treatment of VT. Earlier application of specific treatment procedures such as EPS may be considered for differential diagnosis and curative treatment.
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Adem Kaya (2021) conducted a case report in Ventricular Tachycardia and Wolff-Parkinson-White Syndrome (n=1). Electrical cardioversion and catheter ablation vs. Medical cardioversion (amiodarone) was evaluated on Restoration of normal sinus rhythm and definitive treatment. In a 32-year-old male with ventricular tachycardia and quetiapine use, electrical cardioversion successfully restored sinus rhythm after medical cardioversion failed, followed by curative catheter ablation for Wolff-Parkinson-White syndrome.
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