Key result
General anesthesia with a halogenated agent was associated with a higher rate of postoperative hematocrit decrease ≥5 vol% compared to regional anesthesia (23.8% vs 6.7%, p=0.018).
Why the study?
Does general anesthesia with a halogenated agent increase blood loss in women undergoing elective repeat cesarean section compared to regional anesthesia?
Population
117 singleton term, nonlaboring women undergoing uncomplicated elective repeat low transverse cesarean…
Comparison
General anesthesia using a halogenated agent vs Regional anesthesia (spinal/epidural) (n=75)
Design
Cohort
Follow-up
postoperative
Authors
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Should not change anesthesia selection for cesarean delivery; hypothesis-generating and needs randomized confirmation.
Cohort (n=117)
Does general anesthesia with a halogenated agent increase blood loss in women undergoing elective repeat cesarean section compared to regional anesthesia?
Absolute Event Rate: 23.8% vs 6.7%
p-value: p=0.018
General anesthesia with a halogenated agent during elective repeat cesarean section is associated with a statistically significant but clinically insignificant increase in blood loss compared to regional anesthesia.
Andrews et al. (1992) conducted a cohort in Elective repeat cesarean section (n=117). General anesthesia using a halogenated agent (isoflurane) vs. Regional anesthesia (spinal/epidural) was evaluated on Postoperative decrease in hematocrit of 5 vol% or more (p=0.018). General anesthesia with a halogenated agent was associated with a higher rate of postoperative hematocrit decrease ≥5 vol% compared to regional anesthesia (23.8% vs 6.7%, p=0.018).
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