Key result
A 54-year-old woman with locally advanced rectosigmoid junction cancer developed Takotsubo cardiomyopathy postoperatively, highlighting cancer and its treatment as potential triggers.
Why the study?
Takotsubo cardiomyopathy occurs more frequently in cancer patients due to the inflammatory state, emotional stress of diagnosis, and physical stress of invasive procedures.
Case Report (n=1)
Cancer and its associated physical and emotional stress can trigger Takotsubo cardiomyopathy, highlighting the need for careful cardiological assessment during cancer treatment.
Alerts clinicians to Takotsubo cardiomyopathy risk in perioperative cancer care; hypothesis-generating and leaves causal role open for prospective study.
Background. takotsubo cardiomyopathy (tcm) occurs more frequently in cancer patients than in the general population. The triggers for tcm in cancer patients include not only the inflammatory state of the cancer itself, but also the significant emotional stress of a cancer diagnosis and the physical stress associated with invasive diagnostic and treatment procedures. Case presentation. We describe the case of a 54-yearold woman with histologically verified rectosigmoid junction cancer (cT4bcN2M0) complicated by acute intestinal obstruction. In the early postoperative period, a sudden drop in blood pressure, t-wave inversion and Qt-interval prolongation on ecg, decrease in the left ventricle contractility and presence of wall motion abnormalities on echocardiography (ecHo), as well as an increase in biomarkers of myocardial damage were initially regarded as acute coronary syndrome, which was subsequently excluded according to the findings of coronary angiography, which did not reveal coronary artery obstruction. taking into account the rapid and complete inverse dynamics of changes, acute myocardial infarction without coronary artery obstruction and acute myocarditis were excluded. Ultimately, the diagnosis of takotsubo cardiomyopathy was established. Conclusion. this case report indicates that cancer can be a trigger for the development of tcm; therefore, the assessment of cardiological status and timely detection of cardiac complications in cancer patients during cancer treatment is extremely important and is aimed at increasing the overall survival in this category of patients.
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Alekseev et al. (2023) conducted a case report in Takotsubo cardiomyopathy and rectosigmoid junction cancer (n=1). Cancer and surgical stress was evaluated on Development of Takotsubo cardiomyopathy. A 54-year-old woman with locally advanced rectosigmoid junction cancer developed Takotsubo cardiomyopathy postoperatively, highlighting cancer and its treatment as potential triggers.
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