Key result
Supportive care resolves acute yellow oleander cardiac glycoside toxicity and severe hypomagnesemia.
Case Report (n=1)
No
Yellow oleander poisoning can present with life-threatening bradycardia and hypomagnesemia, which may be successfully managed with supportive care and electrolyte correction in resource-limited settings.
Supports supportive care for oleander toxicity in select cases; leaves open need for prospective validation of protocols.
This case report presents a 29-year-old female who intentionally ingested three yellow oleander ( Thevetia peruviana ) seeds, resulting in acute cardiac glycoside toxicity. The patient presented with gastrointestinal and cardiovascular symptoms, including persistent vomiting, chest discomfort and bradycardia. Notably, the patient also exhibited hypomagnaesemia, an electrolyte disturbance not commonly highlighted in oleander poisoning cases. Through prompt supportive care, careful monitoring and electrolyte management, the patient recovered without the need for digoxin-specific antibody fragments. This case highlights the importance of recognising and managing oleander poisoning, a potentially life-threatening condition that mimics digitalis toxicity, while also emphasising the role of magnesium in cardiac function.
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Thakre et al. (2025) conducted a case report in Yellow oleander poisoning (n=1). Yellow oleander seeds was evaluated. Intentional ingestion of yellow oleander seeds in a 29-year-old female resulted in acute cardiac glycoside toxicity and hypomagnesemia, which successfully resolved with supportive care.
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