Peyer's Patch Dendritic Cells Capturing Oral Antigen Interact with Antigen‐Specific T Cells and Induce Gut‐Homing CD4+CD25+ Regulatory T Cells in Peyer's Patches

Antigen-specific naive T cells accumulated in Peyer's patches only after the feeding of antigen. DCs that captured oral antigen interacted with these T cells in the IFR of PP. Some of these T cells acquired a similar phenotype to CD4(+) CD25(+) regulatory T cells and CCR9(+) gut-homing T cells.