Key result
Low-dose aspirin therapy from early pregnancy did not significantly change the proportion of small for gestational age fetuses in women with late-onset preeclampsia (28% vs 23%; p=0.62).
Why the study?
Does low-dose aspirin therapy prescribed from early in pregnancy modify the severity of late-onset preeclampsia in pregnant women?
Cohort
No
Does low-dose aspirin therapy prescribed from early in pregnancy modify the severity of late-onset preeclampsia in pregnant women?
Absolute Event Rate: 28% vs 23%
p-value: p=.62
Early use of low-dose aspirin in high-risk pregnancies does not modify the clinical severity of late-onset preeclampsia compared to low-risk pregnancies without aspirin.
Early low-dose aspirin showed no SGA reduction in late-onset preeclampsia; leaves open effects on overall disease severity.
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Lan et al. (2018) conducted a cohort in Late-onset preeclampsia. Low-dose aspirin (LDA) therapy vs. No LDA therapy was evaluated on Proportion of foetuses that were small for gestation age (< 10th centile) (p=.62). Low-dose aspirin therapy from early pregnancy did not significantly change the proportion of small for gestational age fetuses in women with late-onset preeclampsia (28% vs 23%; p=0.62).
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