What question did this study set out to answer?

To establish new reference ranges for serial measurements of umbilical vein blood flow during the second half of pregnancy.

January 1, 2005Prenatal Diagnosis

Reference ranges for umbilical vein blood flow in the second half of pregnancy based on longitudinal data

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To establish new reference ranges for serial measurements of umbilical vein blood flow during the second half of pregnancy.
Conducted a prospective longitudinal study measuring umbilical vein diameter and blood flow velocities at four-weekly intervals from 19 to 42 weeks of gestation in 130 low-risk singleton pregnancies.
Evaluated 511 sets of serial observations using regression analysis and multilevel modeling to calculate percentiles for diameter, velocity, volume flow, and weight-normalized flow.
Absolute umbilical vein blood flow demonstrated a continuous increase until term, whereas blood flow normalized per unit of fetal weight showed a corresponding reduction.
Calculations of blood flow based on intensity-weighted mean velocity versus 0.5 of maximum velocity yielded nearly interchangeable results across most fetuses.
Longitudinally derived reference percentiles differed from previous cross-sectional curves, particularly in developmental patterns approaching term.

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Implication

Prospective study reveals gestational reference ranges for umbilical vein blood flow in low-risk pregnancies, indicating improved accuracy for serial fetal monitoring.

Cite This Study

Acharya et al. (2005) studied this question.

synapsesocial.com/papers/6a9c3f3d57420109d4cb0472 https://doi.org/10.1002/pd.1091

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Implication

Prospective study reveals gestational reference ranges for umbilical vein blood flow in low-risk pregnancies, indicating improved accuracy for serial fetal monitoring.

Reference ranges for umbilical vein blood flow in the second half of pregnancy based on longitudinal data

Key Points

Discussion

Implication

Cite This Study

Reference ranges for umbilical vein blood flow in the second half of pregnancy based on longitudinal data

Key Points

Discussion

Implication

Cite This Study

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