Key result
The heart utilizes numerous mechanisms to delicately balance systemic and coronary blood flow demands, overcoming the paradoxical restriction of its own blood supply during peak contraction.
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Design
Review
The paper discusses the physiological mechanisms by which the heart balances systemic and coronary blood flow demands despite restricting its own supply during peak contraction.
Paradoxically the heart, which is solely dedicated to supplying blood to the organs, restricts its own blood supply during peak contraction (Figure 1). To overcome this restriction, the heart has numerous mechanisms which delicately balance the blood flow demands of the systemic and coronary circulation.
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Davies et al. (2008) studied this question. The heart utilizes numerous mechanisms to delicately balance systemic and coronary blood flow demands, overcoming the paradoxical restriction of its own blood supply during peak contraction.
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