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A I7-year-old patient attempted suicide with a massive digoxin overdose. Peak serum digoxin level was 35 ng/ml. Half-life of digoxin was I3 hours which is in contrast to the usual therapeutic half-life of approximately 36 hours. Pronounced hyperkalaemia, peaking at 8-2 mEqll., was noted I4 hours after ingestion.
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Rumack et al. (1974) studied this question.
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