Key result
Remifentanil fast-track anesthesia is linked to shorter ventilation and hospital stays vs conventional anesthesia in VSD closure.
Why the study?
To evaluate the analgesic and sedative effects of remifentanil-based fast-track cardiac anesthesia in children undergoing transthoracic device closure of ventricular septal defects.
Does remifentanil-based fast-track cardiac anesthesia improve postoperative outcomes in children undergoing transthoracic device closure of ventricular septal defects?
Cohort (n=62)
Does remifentanil-based fast-track cardiac anesthesia improve postoperative outcomes in children undergoing transthoracic device closure of ventricular septal defects?
Remifentanil-based fast-track anesthesia is safe and effectively reduces mechanical ventilation time and hospital stay in children undergoing VSD closure.
May inform fast-track protocols in pediatric VSD repair; leaves open confirmation by RCTs before practice change.
BACKGROUND: This study aimed to evaluate the analgesic and sedative effects of remifentanil-based fast-track cardiac anesthesia in children undergoing transthoracic device closure of ventricular septal defects (VSDs). METHODS: A retrospective analysis was conducted on 62 children who underwent transthoracic device closure of VSDs from May 2019 to August 2019. The patients were divided into two groups based on the anesthesia methods: group F was given remifentanil-based fast-track cardiac anesthesia, and Group C was given conventional anesthesia. Patient-related clinical data, postoperative analgesia scores, and sedation scores were collected and analyzed. RESULTS: There was no significant difference in intraoperative hemodynamic changes, bispectral index values, postoperative analgesia scores, sedation scores, or the incidence of adverse events between the two groups. Compared with Group C, the duration of mechanical ventilation and the length of intensive care unit (ICU) and hospital stay in group F were significantly lower. CONCLUSION: Remifentanil-based fast-track anesthesia can be safely applied in children undergoing transthoracic device closure of VSDs, with acceptable postoperative analgesia and sedation effects and shorter mechanical ventilation times and ICU and hospital stays compared with conventional anesthesia.
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Xu et al. (2021) conducted a cohort in Ventricular septal defects (VSDs) (n=62). Remifentanil-based fast-track cardiac anesthesia vs. Conventional anesthesia was evaluated on Postoperative analgesia scores, sedation scores, duration of mechanical ventilation, and length of ICU and hospital stay. Remifentanil-based fast-track anesthesia significantly reduced mechanical ventilation duration, ICU stay, and hospital stay compared with conventional anesthesia in children undergoing VSD closure.
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