Key result
Myotonic muscular dystrophy was associated with twice the abdominal muscle EMG activity compared to controls at the same inspiratory pressure, alongside asynchronous chest wall motion.
Why the study?
How does abdominal muscle recruitment and chest wall motion during inspiratory resistance breathing differ between subjects with myotonic muscular dystrophy and normal controls?
Population
20 subjects: 10 with myotonic muscular dystrophy (MMD) and 10 normal control subjects.
Comparison
Increasing levels of inspiratory resistance… vs Normal control subjects
Design
Case-control
Authors
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May indicate compensatory mechanisms in myotonic dystrophy; hypothesis-generating for respiratory outcomes, with no practice change warranted.
Case-Control (n=20)
How does abdominal muscle recruitment and chest wall motion during inspiratory resistance breathing differ between subjects with myotonic muscular dystrophy and normal controls?
Subjects with myotonic muscular dystrophy exhibit altered abdominal muscle recruitment and chest wall motion during inspiratory resistance breathing compared to normal controls.
Ugalde et al. (2001) conducted a case-control in Myotonic muscular dystrophy (n=20). Myotonic muscular dystrophy vs. Healthy controls was evaluated on Abdominal muscle recruitment (EMG activity) and chest wall motion. Myotonic muscular dystrophy was associated with twice the abdominal muscle EMG activity compared to controls at the same inspiratory pressure, alongside asynchronous chest wall motion.
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