Key result
Non-CAD severe heart failure patients classified as high-risk by the heart failure survival score had a significantly higher risk for sudden cardiac arrest than all other groups (P<.001).
Why the study?
Does the Heart Failure Survival Score (HFSS) predict sudden cardiac arrest in patients with severe heart failure based on etiology?
Cohort (n=712)
Does the Heart Failure Survival Score (HFSS) predict sudden cardiac arrest in patients with severe heart failure based on etiology?
The Heart Failure Survival Score is a useful tool for identifying a subgroup of patients with severe nonischemic heart failure who are at very high risk for sudden cardiac arrest.
HFSS may refine SCA risk stratification in non-CAD severe HF; hypothesis-generating and should not yet change practice.
The authors wanted to investigate whether the heart failure survival score (HFSS) is useful for sudden cardiac arrest (SCA) risk stratification and whether there is a difference with regard to congestive heart failure (CHF) etiology. Data of 712 severe CHF patients (New York Heart Association III/IV 58%/42%, mean age 62+/-8 years, mean left ventricular ejection fraction 26%+/-11%) during the period from 1993-2003 were analyzed. The HFSS was calculated using the Aaronson formula. SCA-free survival was calculated using Kaplan-Meier analysis according to the etiology of CHF: coronary artery disease (CAD) (n=317) vs no CAD (n=395). In regard to SCA risk, the authors found no significant overall difference between patients with or without CAD. Non-CAD HFSS high-risk patients had a significantly higher risk for SCA than all the other groups ( P<.001). The HFSS is useful for the detection of a subgroup of non-CAD severe CHF patients at very high risk for SCA.
No takes yet. Share an insight, caveat, or question.
Castel et al. (2009) conducted a cohort in Severe congestive heart failure (n=712). Heart failure survival score (HFSS) vs. Other HFSS risk groups and CAD patients was evaluated on Sudden cardiac arrest (SCA) (p=<.001). Non-CAD severe heart failure patients classified as high-risk by the heart failure survival score had a significantly higher risk for sudden cardiac arrest than all other groups (P<.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: