Key result
Among hospitalized children with nonbacterial acute gastroenteritis, enteric viruses were identified in 81.7% of cases, with rotavirus being the most common (30.4%) and associated with higher disease severity.
Observational (n=257)
No
Rotavirus and mixed viral infections are the leading causes of severe acute gastroenteritis in hospitalized children in Northern Taiwan.
Supports rotavirus vaccination priorities in hospitalized children; leaves open generalizability from this cross-sectional Northern Taiwan cohort.
By reverse transcription-PCR or PCR, among 257 children with nonbacterial acute gastroenteritis (AGE), rotavirus, norovirus, astrovirus, enteric adenovirus, and multiple viruses were identified in 78 (30.4%), 21 (8.2%), 7 (2.7%), 51 (19.8%), and 53 (20.6%) patients, respectively. Higher disease severity was found for AGE caused by multiple viruses and by rotavirus alone. The majority of rotaviruses isolated from 2004 to 2006 belonged to genotypes G1 (20.4%), G2 (16.5%), G3 (27.2%), and G9 (21.4%).
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Chen et al. (2007) conducted an observational in Acute gastroenteritis (n=257). Enteric viral infection was evaluated on Detection of enteric viruses in fecal specimens. Among hospitalized children with nonbacterial acute gastroenteritis, enteric viruses were identified in 81.7% of cases, with rotavirus being the most common (30.4%) and associated with higher disease severity.
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