Two Cases of Primary Pulmonary Hypertension With Sudden Death Associated With the Administration of Barbiturates

Case Reports1 August 1955TWO CASES OF PRIMARY PULMONARY HYPERTENSION WITH SUDDEN DEATH ASSOCIATED WITH THE ADMINISTRATION OF BARBITURATESSCOTT R. INKLEY, M.D., LOUIS GILLESPIE JR., ROBERT K. FUNKHOUSER, M.D.SCOTT R. INKLEY, M.D., LOUIS GILLESPIE JR., ROBERT K. FUNKHOUSER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-2-396 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe syndrome of pulmonary hypertension in the absence of apparent parenchymal lung disease or primary cardiovascular defects has been diagnosed clinically with increasing frequency since the technic of a cardiac catheterization has become widely available. The clinical picture and pathologic physiology have recently been comprehensively reviewed by Dresdale.1 It is the purpose of this paper to report two cases which have been confirmed at autopsy, and to call attention to the untoward reaction to barbiturate anesthesia which occurred in both patients.CASE REPORTSCase 1. A 41 year old white female was admitted to University Hospitals for the third time...Bibliography1. DresdaleSchultzMichtom TMRJ: Primary pulmonary hypertension. I. Clinical and hemodynamic study, Am. J. Med. 11: 686, 1951. CrossrefMedlineGoogle Scholar2. GilmourEvans JRW: Primary pulmonary hypertension, J. Path. and Bact. 58: 687, 1946. CrossrefMedlineGoogle Scholar3. CrossKobayshi KRCK: Primary pulmonary vascular sclerosis, Am. J. Path. 17: 155, 1947. CrossrefGoogle Scholar4. BrillKrygier ICJJ: Primary pulmonary vascular sclerosis, Arch. Int. Med. 68: 560, 1941. CrossrefGoogle Scholar5. Johnson SR: The effect of some anaesthetic agents on the circulation in man, Acta chir. Scandinav. Supplement 158, 1951. Google Scholar6. SancettaLynnSimeoneScott SRBFRW: Hemodynamic changes following spinal anaesthesia, Circulation 6: 569, 1952. Google Scholar7. WinchellTaylorChapman PHLCB: Effects of Amytal on cardiac output and peripheral resistance of man, Circulation 4: 229, 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication June 19, 1954.From the Department of Medicine, Western Reserve School of Medicine, and The University Hospitals of Cleveland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPULMONARY HYPERTENSIONPrimary pulmonary hypertension: prolonged cardiac arrest and successful resuscitation following induction of anesthesia for heart-lung transplantationAnaesthetic Management for Laparoscopic Sterilisation and Termination of Pregnancy in a Patient with Severe Primary Pulmonary HypertensionNatural history of pulmonary hemodynamics in primary pulmonary hypertensionLong-term follow-up in primary pulmonary hypertension.Death from Rectal ThiopentalThe Familial Occurrence of Primary Pulmonary HypertensionJAMES D. ROGGE, MARVIN E. MISHKIN, PASQUALE D. GENOVESE, M.D., F.A.C.P.GENERAL ANESTHETICS AND ADJUVANTSPrimäre pulmonale HypertensionAn etiologic concept concerning the obscure myocardiopathiesPrimary Pulmonary HypertensionOn the Cause of Syncope and Sudden Death in Primary Pulmonary HypertensionTHOMAS N. JAMES, M.D., F.A.C.P.PRIMARY PULMONARY HYPERTENSION: REPORT OF SIX CASES AND REVIEW OF LITERATURE*†PAUL N. YU, M.D., F.A.C.P.Pitfalls in the diagnosis of pulmonary hypertensionPrimary pulmonary systolic hypertension associated with aneurysm of pulmonary arteryIdiopathic pulmonary hypertension: Etiology, pathogenesis, diagnosis and treatmentPrimary pulmonary hypertensionEFFECTS OF METHYPRYLON (NOLUDAR) AND PHENOBARBITAL ON THE ELECTROCARDIOGRAMESSENTIAL PULMONARY HYPERTENSION: A REPORT OF CLINICAL-PHYSIOLOGIC STUDIES IN THREE PATIENTS, WITH DEATH FOLLOWING CATHETERIZATION OF THE HEART*H. SCHAFER, M.D., J. M. BLAIN, M.D., R. CEBALLOS, M.D., R. J. BING, M.D., F.A.C.P. 1 August 1955Volume 43, Issue 2Page: 396-406KeywordsAnesthesiaCatheterizationHeart diseasesHospital medicineHypertensionIschemiaLungsPolycythemiaPulmonary diseasesPulmonary hypertension ePublished: 1 December 2008 Issue Published: 1 August 1955 PDF downloadLoading ...