We report on a case where a digit of a previously replanted hand was amputated 3 years after injury. Histologically, the finger arteries demonstrated a marked intimal thickening due to fibromuscular proliferation, with narrowing of the lumen. The media showed muscular hyperplasia and fibrosis, whereas the adventitia was normal. These changes are probably a consequence of ischemia and reperfusion injury and might explain the persistent vasomotor insufficiency found in replantation patients.
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Meuli‐Simmen et al. (1996) studied this question.
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