Key result
The evaluation of five major biomarkers, including cortisol/melatonin rhythms, FAAH, LMR, TGF-beta, and ANP/ET-1 ratio, is proposed as a routine laboratory analysis for preventive medicine.
Why the study?
Future laboratory analyses require identifying clinical parameters that involve major integrative biological functions to predict metabolic alterations and systemic disease occurrence.
This review proposes a set of five neuroendocrine and immune biomarkers to evaluate overall health status and predict the onset of cardiovascular and neoplastic diseases.
Answers are grounded in this paper and cite their sources.
May inform preventive cardiology risk assessment; leaves open prospective validation before routine biomarker use.
The future of laboratory analyses would require the identification of clinical parameters involving the main integrative biological functions including neuroendocrine, immune and cardiovascular systems, and capable of predicting the evidence of metabolic alterations and the possible occurrence of systemic diseases
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Lissoni et al. (2019) conducted a review in Cancer and cardiovascular diseases. Biochemical biomarkers (cortisol/melatonin rhythms, FAAH, LMR, TGF-beta, ANP/ET-1 ratio) was evaluated. The evaluation of five major biomarkers, including cortisol/melatonin rhythms, FAAH, LMR, TGF-beta, and ANP/ET-1 ratio, is proposed as a routine laboratory analysis for preventive medicine.
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