Key result
Leukoaraiosis in stroke patients was associated with older age, longer duration of hypertension, mean diastolic blood pressure, and a higher likelihood of lacunar infarcts.
Observational (n=89)
In stroke patients, leukoaraiosis is associated with chronic hypertensive changes and lacunar infarcts rather than cortical or subcortical infarcts.
Supports further research on hypertension control in stroke; hypothesis-generating and should not yet change practice.
Nonspecific periventricular white matter lucencies on computed tomograms (leukoaraiosis) were found in 49 (55%) of 89 stroke patients. We compared the vascular risk factors and the types of stroke with and without leukoaraiosis. Patients with leukoaraiosis were significantly older than those without it. The duration of hypertension was longer than those without leukoaraiosis. Mean diastolic blood pressure was associated with leukoaraiosis. No association was found with systolic blood pressure, diabetes mellitus, angina pectoris, myocardial infarction, heart failure, valvular disease and intermittent claudication. Patients with leukoaraiosis were significantly more likely to have lacunar infarcts on computed tomograms but were less likely to have cortical infarcts, subcortical infarcts or cerebral hemorrhage.
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Karşıdağ et al. (1995) conducted an observational in Stroke (n=89). Leukoaraiosis vs. No leukoaraiosis was evaluated on Vascular risk factors and types of stroke. Leukoaraiosis in stroke patients was associated with older age, longer duration of hypertension, mean diastolic blood pressure, and a higher likelihood of lacunar infarcts.
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