Key result
Leukoaraiosis was significantly associated with higher mean carotid intima-media thickness (P=0.002) and the presence of carotid plaques (P=0.007) in ischemic stroke patients.
Why the study?
Is leukoaraiosis associated with carotid atherosclerosis markers (IMT and plaques) in patients with ischemic stroke or TIA?
Population
170 consecutive patients with ischemic stroke or transient ischemic attack (TIA)
Design
Cross-sectional
Authors
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Supports shared atherosclerotic mechanisms in stroke; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=170)
Is leukoaraiosis associated with carotid atherosclerosis markers (IMT and plaques) in patients with ischemic stroke or TIA?
p-value: p=0.002
Leukoaraiosis is independently associated with increased carotid intima-media thickness and carotid plaques in patients with ischemic stroke or TIA, suggesting an underlying atherosclerotic pathophysiology.
Bénassayag et al. (2012) conducted a cross-sectional in Ischemic stroke or transient ischemic attack (TIA) (n=170). Leukoaraiosis (LA) vs. Absence of leukoaraiosis was evaluated on Mean carotid intima-media thickness (IMT) and presence of carotid plaque (p=0.002). Leukoaraiosis was significantly associated with higher mean carotid intima-media thickness (P=0.002) and the presence of carotid plaques (P=0.007) in ischemic stroke patients.
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