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May 6, 1978BMJOpen Access

Production of ischaemic cardiac pain by nifedipine.

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Key result

Administration of thiopentone, suxamethonium, and halothane induced recurrent angioneurotic oedema and plasma C3 conversion in a single patient.

Population

A single patient undergoing anesthesia

Design

Case_report

Authors

AJA G JariwallaOrpington HospitalEAEric Gary AndersonBridge University

Discussion

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Overview

May caution against these agents in susceptible patients; leaves open complement activation mechanisms and generalizability.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A single male patient who experienced recurrent angioneurotic oedema and C3 conversion following administration of anesthetic agents.
E
Exposure
Administration of anesthetic agents (Althesin, thiopentone, suxamethonium, halothane)
O
Outcome
Adverse reactions including hypotension, angioneurotic edema, and lip swellingsafety

This case report highlights the potential for severe allergic or anaphylactoid reactions, including C3 conversion, following the administration of certain anesthetic agents.

Cite This Study

Jariwalla et al. (1978) conducted a case report in Anaphylactoid reaction to anesthetics (n=1). Anesthetic agents (thiopentone, suxamethonium, halothane) was evaluated on Adverse reaction (angioneurotic oedema, hypotension, C3 conversion). Administration of thiopentone, suxamethonium, and halothane induced recurrent angioneurotic oedema and plasma C3 conversion in a single patient.

synapsesocial.com/papers/6a9c60ac653121bb2822427fhttps://doi.org/10.1136/bmj.1.6121.1181
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Also Consider

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  4. 4Sufentanil Does Not Block Sympathetic Responses to Surgical Stimuli in Patients Having Coronary Artery Revascularization Surgery1990 · 22 citations
  5. 5Case Report: Sympathetic crashing acute pulmonary edema – only “NIV and nitroglycerin”?2024