Answers are grounded in this paper and cite their sources.
[reaction: see text] A highly convergent asymmetric synthesis of the masked southern segment of the antimitotic agent disorazole A(1) involves a Sonogashira coupling between a C1'-C10' enyne and a suitably protected C11'-C19' vinyl iodide. The central E,Z,Z-triene moiety is masked as a more stable ynediene.
No takes yet. Share an insight, caveat, or question.
Hartung et al. (2002) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: