Adverse Effects of ACE Inhibitors

Letters15 February 1993Adverse Effects of ACE InhibitorsTheodore J. Chu, MD and Norman Chow, MDTheodore J. Chu, MDSearch for more papers by this author and Norman Chow, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-4-199302150-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:A wide range of adverse effects such as cough and angioneurotic edema [1] may result from the use of ACE inhibitors [2]. Rarely, angioedema has been reported to occur up to 3 years after initiation of therapy [3]. We describe a patient who took captopril for 7 years before onset.A 55-year-old woman who had taken captopril, 25 mg thrice daily, for hypertension since 21 August 1984 had two episodes of moderate tongue swelling in August and September 1991, respectively. On 14 October 1991, she awoke with a severely swollen tongue. Examination showed that she was drooling, ...References1. Israili ZH, Hall WD. Cough and angioneurotic edema associated with angiotensin-converting enzyme inhibitor therapy. Ann Intern Med. 1992; 117:234-42. Google Scholar2. Weber MA. Safety issues during antihypertensive treatment with angiotensin converting enzyme inhibitors. Am J Med. 1988; 84(Suppl 4A):16-23. Google Scholar3. Chin HL, Buchan DA. Severe angioedema after long-term use of an angiotensin-converting enzyme inhibitor (Letter). Ann Intern Med. 1990; 112:312-3. Google Scholar Author, Article, and Disclosure InformationAuthors: Theodore J. Chu, MD; Norman Chow, MD PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAntihypertensive DrugsIncidence and Predictors of Angioedema in Elderly Hypertensive Patients at High Risk for Cardiovascular Disease: A Report From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)Adverse Dermatologic Effects of Cardiovascular Drug Therapy: Part IIAngiotensin-converting enzyme (ACE) inhibitors and angio-oedemaAngiotensin converting enzyme inhibitors and the otolaryngologistCaptopril 15 February 1993Volume 118, Issue 4 Page: 314-315 Keywords ACE inhibitors Drug therapy Edema Emergency department Epinephrine Esterases Food allergies Hypertension Inflammation Tongue ePublished: 15 August 2000 Issue Published: 15 February 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...