Key result
Balloon aortic valvuloplasty successfully reduced the transvalvular pressure gradient from 80 mmHg to 44 mmHg in a 1493 g premature neonate with critical aortic valve stenosis.
Why the study?
Does balloon aortic valvuloplasty improve transvalvular pressure gradient and clinical condition in a premature neonate with critical aortic valve stenosis weighing 1493 g?
Case Report (n=1)
Does balloon aortic valvuloplasty improve transvalvular pressure gradient and clinical condition in a premature neonate with critical aortic valve stenosis weighing 1493 g?
Balloon aortic valvuloplasty is feasible and effective as a first-line treatment for critical aortic valve stenosis in very low birth weight premature neonates.
BAV feasible in this 1493 g neonate; hypothesis-generating for very low birth weight critical AS and should not yet change practice.
The use of balloon aortic valvuloplasty for congenital aortic valve stenosis was well established in literatures. However, balloon aortic valvuloplasty performed in low body weight neonates had been infrequently reported. Here we report a 5-day-old premature neonate diagnosed critical aortic valve stenosis. Balloon aortic valvuloplasty was performed as first-line therapy while the patient weighed only 1493 g. Balloon aortic valvuloplasty went successfully with transvalvular pressure gradient decreased from 80 mmHg to 44 mmHg. Aortic regurgitation after balloon aortic valvuloplasty was mild. The patient's clinical condition stabilized after balloon aortic valvuloplasty and was able to gain weight to 2665 g. Our report demonstrates that balloon aortic valvuloplasty is possible, safe and efficient as first-line approach for critical aortic valve stenosis in neonates with low body weight.
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Lin et al. (2018) conducted a case report in Critical aortic valve stenosis (n=1). Balloon aortic valvuloplasty was evaluated on Transvalvular pressure gradient. Balloon aortic valvuloplasty successfully reduced the transvalvular pressure gradient from 80 mmHg to 44 mmHg in a 1493 g premature neonate with critical aortic valve stenosis.
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