Why the study?
Does anterograde double-balloon valvoplasty improve hemodynamics in a premature baby with severe aortic stenosis?
Does anterograde double-balloon valvoplasty improve hemodynamics in a premature baby with severe aortic stenosis?
Anterograde double-balloon valvoplasty using coronary angioplasty catheters is a feasible and effective treatment for severe aortic stenosis in extremely low birth weight premature infants.
Sustained hemodynamic result in this extremely low birth weight infant; leaves open generalizability and safety in larger prospective series.
We describe our treatment of a premature baby born weighing 1400 g with severe aortic stenosis, with a gradient of 80 mmHg across the valve. Efforts to advance a 6 mm angioplasty catheter into the stenotic aortic valve via the left ventricle failed. Anterograde angioplasty, instead, was performed using two 4 mm coronary angioplasty catheters. Six months subsequent to the intervention, the pressure gradient measured 25 mmHg, and there was no hemodynamically significant aortic insufficiency.
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Peuster et al. (2000) studied this question.
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