Key result
Fetal aortic balloon valvuloplasty successfully treated two fetuses with critical aortic stenosis and severe mitral regurgitation, eliminating the need for postnatal cardiac interventions.
Why the study?
Fetuses with critical aortic stenosis, severe mitral regurgitation, and left atrial enlargement are at risk of developing heart failure and intrauterine death.
Does fetal aortic balloon valvuloplasty prevent the need for postnatal cardiac interventions in fetuses with critical aortic stenosis and severe mitral regurgitation?
Case Report (n=2)
No
Does fetal aortic balloon valvuloplasty prevent the need for postnatal cardiac interventions in fetuses with critical aortic stenosis and severe mitral regurgitation?
Fetal aortic valvuloplasty can serve as a definitive treatment for fetuses with critical aortic stenosis and severe mitral regurgitation, potentially avoiding the need for postnatal interventions.
Answers are grounded in this paper and cite their sources.
Fetal aortic valvuloplasty may avoid postnatal intervention in select cases; hypothesis-generating and should not yet change practice.
Fetuses with critical aortic stenosis, severe mitral regurgitation and left atrial enlargement are at risk to develop heart failure and intrauterine death. We present two cases with this physiology who underwent fetal aortic balloon valvuloplasty at 25 + 5 and 28 + 2 weeks as their only intervention without requiring postnatal treatment during short- to medium-term follow-up of 1.4 and 4.9 years.
No takes yet. Share an insight, caveat, or question.
Tulzer et al. (2022) conducted a case report in Critical aortic stenosis, severe mitral regurgitation, and giant left atrium (n=2). Fetal aortic balloon valvuloplasty was evaluated on Need for postnatal cardiac interventions or surgeries. Fetal aortic balloon valvuloplasty successfully treated two fetuses with critical aortic stenosis and severe mitral regurgitation, eliminating the need for postnatal cardiac interventions.
Synapse has enriched 10 related papers. Consider them for comparative context: