Key result
Intrauterine aortic valvuloplasty was technically successful in 69.6% of fetuses with critical aortic stenosis, achieving a biventricular circulation postnatally in two-thirds of liveborn cases.
Why the study?
Does intrauterine aortic valvuloplasty improve postnatal biventricular circulation and survival in fetuses with critical aortic stenosis?
Population
23 fetuses with critical aortic stenosis (4 with hydrops), median gestational age 26 + 4 weeks.
Design
Case_series
Follow-up
Postnatal
Authors
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Hypothesis-generating in fetal aortic stenosis; should not change practice pending controlled trials.
Observational (n=23)
Does intrauterine aortic valvuloplasty improve postnatal biventricular circulation and survival in fetuses with critical aortic stenosis?
Intrauterine aortic valvuloplasty in fetuses with critical aortic stenosis can successfully prevent progression to hypoplastic left heart syndrome and achieve biventricular circulation in a majority of successfully treated patients.
Arzt et al. (2011) conducted an observational in Critical aortic stenosis (n=23). Intrauterine aortic valvuloplasty was evaluated on Technical success of the procedure. Intrauterine aortic valvuloplasty was technically successful in 69.6% of fetuses with critical aortic stenosis, achieving a biventricular circulation postnatally in two-thirds of liveborn cases.
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