Key result
Having maternal laparotomy available as an option significantly increased the technical success of fetal aortic valvuloplasty compared to a percutaneous-only approach (83.3% vs. 20.0%, P=0.017).
Why the study?
Does having maternal laparotomy as an option improve the technical success of fetal aortic valvuloplasty in fetuses with critical aortic stenosis?
Population
22 fetuses diagnosed with critical aortic stenosis developing into hypoplastic left heart syndrome (HLHS)
Comparison
Fetal aortic valvuloplasty with maternal… vs Fetal aortic valvuloplasty using only a…
Design
Case_series
Authors
Loading...
Maternal laparotomy option may aid fetal aortic valvuloplasty success; hypothesis-generating from Level 5 data and requires prospective validation.
Observational (n=22)
Does having maternal laparotomy as an option improve the technical success of fetal aortic valvuloplasty in fetuses with critical aortic stenosis?
Absolute Event Rate: 83.3% vs 20%
p-value: p=0.017
Having maternal laparotomy available as an option significantly improves the technical success rate of fetal aortic valvuloplasty for critical aortic stenosis.
Wilkins‐Haug et al. (2006) conducted an observational in Critical aortic stenosis developing into hypoplastic left heart syndrome (HLHS) (n=22). Maternal laparotomy as an option during fetal aortic valvuloplasty vs. Percutaneous approach only was evaluated on Technical success (balloon inflation across the aortic annulus and a broader jet through the aortic valve as assessed by Doppler) (p=0.017). Having maternal laparotomy available as an option significantly increased the technical success of fetal aortic valvuloplasty compared to a percutaneous-only approach (83.3% vs. 20.0%, P=0.017).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: