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March 26, 2020Catheterization and Cardiovascular InterventionsOpen Access

Procedural, pregnancy, and short‐term outcomes after fetal aortic valvuloplasty

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Why the study?

Fetal aortic valvuloplasty (FAV) is performed in severe mid-gestation aortic stenosis to prevent hypoplastic left heart syndrome, but the effect of technical aspects on procedural risks and pregnancy outcomes required evaluation.

Population

108 fetuses with an attempted cardiac puncture for FAV

Comparison

Technical aspects of FAV (such as cannula size and number of punctures)

Design

Registry-based retrospective cohort study

Authors

NPNeil D. PatelSNStephen NageotteFIFrank F. Ing

Discussion

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Overview

Technical success and later gestational age were associated with higher live birth odds; hypothesis-generating and requires prospective trials before practice change.

Structured PICO

P
Population
108 fetuses with severe mid-gestation aortic stenosis who underwent attempted fetal aortic valvuloplasty, mean gestational age 26.1 ± 3.3 weeks, from the International Fetal Cardiac Intervention Registry (2002-2018).
I
Intervention
Fetal aortic valvuloplasty (FAV)
O
Outcome
Procedural risks and pregnancy outcomes (including technical success, intraprocedural complications, and live birth)hard clinical

Fetal aortic valvuloplasty is a high-risk procedure where technical success and later gestational age at intervention significantly increase the odds of live birth, though multiple cardiac punctures increase complication rates.

Cite This Study

Patel et al. (2020) studied this question.

synapsesocial.com/papers/6a8a40b60e1a8f7244fd6c98https://doi.org/10.1002/ccd.28846
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Postnatal outcome following fetal aortic valvuloplasty for critical aortic stenosis2024 · 9 citations
  2. 2Valvuloplasty in 103 fetuses with critical aortic stenosis: outcome and new predictors for postnatal circulation2021 · 58 citations
  3. 3Intrauterine Valvuloplasty in Severe Aortic Stenosis—A Ten Years Single Center Experience2022 · 12 citations
  4. 4Technical Success and Serious Adverse Events for Fetal Aortic Valvuloplasty in a Large 20-Year Cohort2024 · 8 citations
  5. 5Factors affecting technical success of fetal aortic valve dilation2006 · 74 citations